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SURGICAL VALVE SOLUTIONS

EPIC™ MITRAL AND AORTIC TISSUE VALVES

Exceptional hemodynamic performance, lasting durability, and a design that preserves future valve-in-valve treatment options.

SURGICAL VALVE SOLUTIONS

EPIC™ MITRAL AND AORTIC TISSUE VALVES

Exceptional hemodynamic performance, lasting durability, and a design that preserves future valve-in-valve treatment options.

THE FUTURE EXPANDS HERE

The Epic™ Elite valve is CE Mark approved*

Epic™ Elite valves give you the confidence of choosing the precise location of expansion for a future transcatheter aortic or mitral intervention. The expansion zone enables the Epic Elite valve to expand predictably under low pressure (5–9 atm)1 for a larger transcatheter valve implant during a future intervention.

Explore Epic™ Elite Resources


Learn more about future intervention planning and our adaptive cuff technology.
 

View Expansion ZoneView Adaptive Cuff

An epic evolution of nature and design

From the start in 1979, our platform of Epic™ mitral and aortic tissue valves has combined the best nature has to offer with advanced engineering. Over the decades, minor adjustments to our legacy valve were added gradually, evolving the Epic™ platform into the innovative porcine tissue valves trusted by physicians today.

Optimized to support future valve-in-valve* interventions

Mitral

  • Low stent post height and natural porcine leaflet behavior to not form a "curtain" may reduce risk of obstructing left ventricular outflow tract (LVOT)
  • Simplified implantation with ratcheting holder to risk of suture looping while offering one-cut release

Aortic

  • Low stent post height may reduce risk of coronary obstruction
  • Natural porcine leaflet behavior to not form a "curtain" may reduce need for risky leaflet modification procedures

     

*Note: The safety and effectiveness of valve-in-valve procedures in Epic™ valves has not been established.

10 Years

97.3 ± 0.5%

Freedom from
surgery for SVD,
all patient ages
(Epic™ aortic valve)3

10 Years

95.7 ± 2.6%

Freedom from
surgery for SVD,
all patient ages
(Epic™ mitral valve)3

15 Years

98.4 ± 0.8%

Freedom from
surgery for SVD
(Epic™ Supra aortic valve)4

Hear how an Epic tissue heart valve impacted both Tom and Dana. Getting them back to doing the things that they love.

Tom

Dana

The platform for possibility

The Epic™ platform has been proven over time and defined by strong hemodynamics, intuitive implantability, a future-forward design and more. The platform boasts the low ventricular protrusion in all valve sizes, a flexible polymer stent, individually selected porcine leaflets to ensure optimal coaptation and a flexible sewing cuff designed to minimize both suture drag and paravalvular leak. Now we offer even more for lifetime management with the Epic™ Elite the addition of an expansion zone - for low pressure, predictable expansion in a future intervention.

 

  • Epic™ Elite aortic valve
    • PORCINE LEAFLETS
    • EXPANSION ZONE
    • ADAPTIVE CUFF
    • UNIQUE PERICARDIAL SHIELD
    • LOW AORTIC PROTRUSION

    • PORCINE LEAFLETS
      Natural leaflet tissue with maximal opening (no muscle bar), complete leaflet coaptation (no central gap), no leaflet curtaining, and less calcification with reduced risk for stroke during reintervention5

    • EXPANSION ZONE
      Expands at specific location at low pressures to accommodate a larger transcatheter valve in a future valve-in-valve procedure1*

    • ADAPTIVE CUFF
      Engineered to:

      • Allow maximum flexibility and easy passage through all anatomies
      • Prevent paravalvular leaks by sealing in all planes and minimize parachuting resistance when delivering the valve onto the annulus

    • UNIQUE PERICARDIAL SHIELD
      Provides a tissue-to-tissue interface to help prevent the risk of abrasion

    • LOW AORTIC PROTRUSION
      Mitigates the risk of coronary obstruction and sinus jailing

      Flexfit™ polymer stent

      • Eases implant
      • Accommodates minimally invasive surgery
      • Reduces leaflet stress by absorbing shock of each heartbeat
    Epic Max
    1
    2
    3
    4
    5

    1. PORCINE LEAFLETS


      Natural leaflet tissue with maximal opening (no muscle bar), complete leaflet coaptation (no central gap), no leaflet curtaining, and less calcification with reduced risk for stroke during reintervention5

    2. EXPANSION ZONE


      Expands at specific location at low pressures to accommodate a larger transcatheter valve in a future valve-in-valve procedure1*

    3. ADAPTIVE CUFF

      Engineered to:

      • Allow maximum flexibility and easy passage through all anatomies
      • Prevent paravalvular leaks by sealing in all planes and minimize parachuting resistance when delivering the valve onto the annulus

    4. UNIQUE PERICARDIAL SHIELD

      Provides a tissue-to-tissue interface to help prevent the risk of abrasion

    5. LOW AORTIC PROTRUSION

      Mitigates the risk of coronary obstruction and sinus jailing

      Flexfit™ polymer stent

      • Eases implant
      • Accommodates minimally invasive surgery
      • Reduces leaflet stress by absorbing shock of each heartbeat

    *Expansion zone available on sizes 19 mm - 27 mm

  • Epic™ Elite mitral valve
    • Optimal Leaflet Design and Matching
    • Ratcheting Holder
    • Flexible Cuff
    • Unique Pericardial Shield
    • FlexFitTM Polymer Stent
    • Low Ventricular Protrusion
    • Expansion zone

    • OPTIMAL LEAFLET DESIGN AND MATCHING
      Reduces regurgitation risk

    • RATCHETING HOLDER
      Streamlines implant, reduces risk of suture looping, and offers true one cut holder release

    • FLEXIBLE CUFF
      Mitigates PVL and easily fits patient anatomy

    • UNIQUE PERICARDIAL SHIELD
      Provides a tissue-to-tissue interface to help prevent the risk of abrasion

    • FLEXFITTM POLYMER STENT

      • Eases implant
      • Accommodates minimally invasive surgery
      • Reduces leaflet stress by absorbing shock of each heartbeat

    • LOW VENTRICULAR PROTRUSION
      Avoids LVOT obstruction

    • EXPANSION ZONE
      Expands at specific location at low pressure to accommodate a larger transcatheter valve in a future valve-in-valve procedure1*

    Epic Plus Supra mitral stented tissue valve features
    2
    3
    4
    5
    6
    7

    1. Optimal leaflet design and matching

      Reduces regurgitation risk

    2. Ratcheting holder

      Streamlines implant, reduces risk of suture looping, and offers true one cut holder release

    3. Flexible cuff

      Mitigates PVL and easily fits patient anatomy

    4. Unique pericardial shield

      Provides a tissue-to-tissue interface to help prevent the risk of abrasion

    5. Flexfit™ polymer stent

      • Eases implant
      • Accommodates minimally invasive surgery
      • Reduces leaflet stress by absorbing shock of each heartbeat

    6. Low ventricular protrusion

      Avoids LVOT obstruction

    7. Expansion zone

      Expands at specific location at low pressure to accommodate a larger transcatheter valve in a future valve-in-valve procedure1*

    *Expansion zone available on sizes 25 mm - 29 mm

  • Low Profile Design for Now and Later

    Curtaining is a characteristic of bioprosthetic valves in which the leaflets, when opened, stand tall or form a “curtain” between stent posts. Epic leaflets are not prone to curtaining, which may result in less LVOT obstruction.

    Leaflet behavior when opened

    Epic™ Plus valve with representative transcatheter stent inserted

    Mitris Resilia‡ Valve with representative transcatheter stent inserted

    ‡Indicates a third-party trademark, which is property of its respective owner.

* CE Number 2797

MAT-2630610 v4.0 | Item approved for OUS use only.

References
  1. Epic™ Elite Instructions for Use
  2. Approval Dates on file at Abbott
  3. Jawad, Khalil, Sven Lehmann, Alex Koziarz, Maja Dieterlen, Stefan Feder, Martin Misfeld, Jens Garbade, Vivek Rao, and Michael Borger. “Midterm results after St Jude Medical Epic porcine xenograft for aortic, mitral, and double valve replacement.” Journal of Cardiac Surgery 35, no. 8 (2020): 1769-1777.
  4. Anselmi, Amedeo, et al. "Porcine bioprostheses for surgical aortic valve replacement: very long-term performance of a third-generation device." Journal of Cardiovascular Medicine 24, no. 8 (2023): 514-521.J.
  5. Keshishi, Melanie, et al. “Comparison of Modes of Failure and Clinical Outcomes Between Explanted Porcine and Bovine Pericardial Bioprosthetic Valves.” Cardiovascular Pathology (2023): 107516.
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MAT-2624683 v24.0 | Item approved for OUS use only.

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