AMPLATZER™ AMULET™ LAA OCCLUDER
Designed to treat patients with non-valvular atrial fibrillation (AF) who are at risk of ischemic stroke, the Amplatzer™ Amulet™ LAA Occluder offers complete closure of the left atrial appendage (LAA) and immediately eliminates the need for oral anticoagulants.1
NOW AVAILABLE IN THE U.S.
THOUSANDS OF PATIENTS TREATED WORLDWIDE
Introducing the first and only LAA occluder that offers immediate freedom from oral anticoagulants (OACs). With unique dual seal technology to ensure immediate and complete closure and the widest range of sizes of any LAA occluder, Amplatzer™ Amulet™ makes closure an option for more patients with atrial fibrillation (AF).1,2
GET THE STUDY RESULTS: AMULET™ VS WATCHMAN‡
‡Indicates a third-party trademark, which is property of its respective owner.

DOES NOT REQUIRE ORAL ANTICOAGULANTS (OACS) AT DISCHARGE
Amplatzer Amulet is the first and only FDA approved LAA occluder that offers immediate freedom from OACs. Finally, closure is an option for patients who1-5:
HAVE HAD A
BLEEDING EVENT
ARE AT HIGH
RISK FOR FALLS
ARE AT RISK FOR
DRUG INTERACTIONS
ARE UNABLE OR UNWILLING TO ADHERE TO ROUTINE MONITORING
DUAL SEAL TECHNOLOGY TO COMPLETELY SEAL THE ORIFICE
Innovative dual seal design, leverages a proven Amplatzer design that has been trusted for over 20 years.1
First: Amplatzer Amulet Occluder conforms to different shapes of LAA anatomy and requires minimal depth for implant.
Second: DISC covers completely the LAA opening - effectively sealing blood flow around the device.
PATIENTS WHO BENEFIT
The first and only LAA Occluder for AF patients and cases like these
Life-long medication to reduce stroke risk is not an option for many patients and many reasons. The Amplatzer™ Amulet™ LAA Occluder permanently closes this primary stroke pathway without requiring these patients to endure the challenges of Oral Anticoagulants (OACs).
- Comorbidities and concerns about drug interactions
OACs are incompatible with treatments for many comorbidities including depression or arthritis. Amplatzer Amulet occluder is an alternative to oral anticoagulants that can increase the risk of drug interactions.
Michael (AGE 75)
Michael has Non-Valvular Atrial Fibrillation (NVAF) and a CHA2DS2-VASc score of 5. He is reducing his stroke risk without increasing his risk for drug interactions.
NVAF patients with comorbidities should know that there is an alternative.
- Adherence or compliance issues
Adverse effects, the cost of Novel Oral Anticoagulants (NOACs), or the monitoring required when taking warfarin, often make compliance a challenge for patients. Amplatzer Amulet occluder is an alternative to life-long oral anticoagulants that can lead to noncompliance.
Sarah (AGE 73)
Sarah has NVAF and a CHA2DS2-VASc score of 4. She is reducing her stroke risk without having to take OACs for the rest of her life.
NVAF patients who struggle with compliance should know that there is an alternative.
- Daily activities that increase bleeding risk
The long-term bleeding risks associated with OACs such as warfarin are particularly concerning for patients with active lifestyles or occupations. Consider Amplatzer Amulet occluder for active patients.
Rita (AGE 65)
Rita has NVAF and a CHA2DS2-VASc score of 4. She is reducing her stroke risk without having to limit her travel and play with her grandchildren.
NVAF patients who want to remain active should know that there is an alternative.
- A history of falls and a high risk of bleeding
A fall can erode a patient’s confidence and willingness to engage in everyday tasks. It can also lead to a major bleeding event. Consider Amplatzer Amulet occluder when you or your patients are concerned about the risk of falls or bleeding.
Nathan (AGE 80)
Nathan, who has NVAF and a CHA2DS2-VASc score of 5, hit his head the last time he fell. He and his doctor want to reduce his stroke risk without increasing his risk for a major bleeding event.
NVAF patients at high risk for bleeding should know that there is an alternative.
- A contraindication to OACs
For patients with poorly controlled or uncontrolled hypertension, oral anticoagulants are contraindicated. Amplatzer Amulet occluder is an alternative to life-long oral anticoagulants that are not a safe choice for these patients.
Regina (AGE 55)
Regina, who has NVAF and a CHA2DS2-VASc score is 4, has had poorly controlled hypertension for 10 years. Her doctor wants to reduce her stroke risk without jeopardizing her safety.
NVAF patients with poorly controlled hypertension should know that there is an alternative.
For educational purposes only; not real patient cases.
KEY FEATURES
The first and only LAA occluder that ensures the best fit across the most diverse range of LAA anatomies1

AMPLATZER™ AMULET™ LAA OCCLUDER
The Amplatzer™ line pioneered the technology of structural heart occlusion devices and remains the leading choice for implanters worldwide. Amplatzer devices, and other life-changing innovations from Abbott, continue to transform futures.
130+
DISCOVERING NEW WAYS TO MAKE LIFE BETTER FOR MORE THAN 130 YEARS2
160+
MAKING A DIFFERENCE
IN OVER 160 COUNTRIES2
109K
EMPLOYEES WORKING AROUND THE WORLD TO MAKE A LASTING IMPACT ON HEALTH2
Get the study results: Amulet™ vs Watchman‡
‡Indicates a third-party trademark, which is property of its respective owner.
MAT-2111179 v2.0 | Item approved for U.S. use only.