STRUCTURAL INTERVENTIONS

AMPLATZER™ TALISMAN™
PFO OCCLUDER

Effective PFO closure is made easier with the Amplatzer™ Talisman™ PFO Occluder.1 For patients who have experienced a PFO-associated stroke, clinical trials have shown that they can benefit from PFO closure.2-4 This minimally-invasive procedure significantly reduces the risk of recurrent ischemic stroke and offers an excellent safety profile.

THE PIONEER 
IN PFO CLOSURE1

As the device that created the category, the Amplatzer™ PFO Occluder has sustained leadership over decades of use by pursuing clinical evidence to become the first device supported by positive PFO trial results.2

Today, it is the most-studied device of its kind, with over 180,000 patients treated worldwide.1 And our clinical evidence is unmatched, thanks to the largest-ever trial for PFO closure, boasting 5,810 patient-years of data.2

About the Amplatzer™ Talisman™
PFO Occluder

With the Amplatzer™ Talisman™ PFO Occluder, the device you know and trust just got better. It is built on the proven Amplatzer PFO closure technology and the Amplatzer Trevisio™ Delivery System, with key enhancements to make it our most advanced and easy-to-use PFO closure device yet:

  • We've added a 30 mm device so you have the complete PFO portfolio for every case
  • The occluder comes assembled and ready to use, simplifying preparation and enhancing ease-of-use

The PFO Occluder trusted by thousands of physicians around the world1

180K+

Global implants1


WE SET THE STANDARD

  • Pioneered treatment with a PFO-specific device
  • Available in over 80 countries around the world

5,810

PATIENT-YEARS OF DATA2


WE RAISE THE BAR

  • With the landmark RESPECT trial,2 we had the most extensive patient follow-up, almost 2x more than other PFO trials
  • RESPECT was also the only trial to include patients on anticoagulation therapy, a real-world cross-section of patients

990

PATIENTS IMPLANTED WITH DEVICE IN RCTS2-4


WE DEMONSTRATE EXCELLENCE

  • ZERO device erosions, thrombus, or embolization events in 6 published trials with 990 patients
  • 94.2% effective closure rate at 6 months

How to implant the Amplatzer Talisman 
PFO Occluder

Watch the Amplatzer™ Talisman™ PFO Occluder implant procedure video.

The Amplatzer™ Talisman™ PFO Occluder is indicated for percutaneous transcatheter closure of a patent foramen ovale (PFO) to reduce the risk of recurrent ischemic stroke in patients, predominantly between the ages of 18 and 60 years, who have had a stroke due to a presumed paradoxical embolism, as determined by a neurologist and cardiologist following an evaluation to exclude other causes of ischemic stroke.

Among patients with a PFO who have had an ischemic stroke, the Amplatzer Talisman PFO Occluder has demonstrated excellent safety and effectiveness in reducing the risk of recurrent stroke.

Key benefits for PFO patients

59% RELATIVE RISK REDUCTION IN RECURRENT ISCHEMIC STROKE5

LESS ANXIETY, MORE PEACE-OF-MIND

For patients who have experienced a PFO-associated stroke, the thought of a recurrence can generate anxiety. Determining and delivering the most effective treatment soon after a stroke is critically important to provide these patients with peace-of-mind.

For patients and caregivers wanting to learn more about PFO-associated stroke and PFO closure, www.PFOstroke.com is an excellent resource, including:

  • All about PFO and stroke
  • Understanding PFO treatment options
  • Information about the Amplatzer Talisman PFO Occluder
  • Resources, including FAQ and brochures
     

One week after her PFO closure, Christine was back on the treadmill running 5 miles an hour - (Christine Lee - USA)

After Christine Lee’s stroke at age 33, her neurologist ordered a transesophageal echocardiogram to look for a PFO. Nearly 6 months after her first stroke, she had a TIA. Her neurologist then made a referral to an interventional cardiologist, and he recommended she get the PFO closure procedure within 7 days.

Hear about her experience
“I’ve had so many emails from readers who say their neurologist won’t make that referral to an interventional cardiologist. They just won’t. They want to know the name of my cardiologist, because they’re so desperate.”

READ MORE


Find a Talisman PFO Certified
Physician Near Me

Use this tool to refer a patient or consult with a certified implanting physician near you.

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FEATURES

Advancing the Gold Standard in PFO Closure

For decades, interventional cardiologists have trusted the Amplatzer™ PFO Occluder for ease-of-use, safety, and excellent clinical outcomes.2 With our latest addition, the Amplatzer™ Talisman™ PFO Occlusion System, the easy-to-use just got easier:

  • We've added a 30mm device so you have the complete PFO portfolio for every case.
  • The occluder comes assembled and ready to use, streamlining preparation and enhancing the user experience.

Often Imitated,
Never Matched

Unique design features set the Amplatzer Talisman PFO Occluder apart from the rest.

*Only the 18 mm size is not asymmetric.
Effective closure.


Minimizing Complexity in PFO Closure

SIMPLIFIED
PREP

Occluder comes assembled to Trevisio™  delivery cable, ready to use
 

RECAPTURABLE AND REPOSITIONABLE

Self-expanding discs align to the PFO without an additional “locking” step and can be adjusted for ideal placement
 

LOW-PROFILE
DELIVERY

8 F and 9 F introducer sheaths enable treatment of patients with smaller vasculature

NEW VERSION AVAILABLE
GET THE AMPLATZER PORTFOLIO APP

The Amplatzer Portfolio App helps physicians determine which Amplatzer Structural Interventions device to use by suggesting applicable devices based on respective Instructions for Use.

MAT-2008367 v5.0 | Item approved for U.S. use only.

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Caution: These products are intended for use by or under the direction of a physician. Prior to use, reference the Instructions for Use, inside the product carton (when available) or at eifu.abbottvascular.com or at medical.abbott/manuals for more detailed information on Indications, Contraindications, Warnings, Precautions and Adverse Events.
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